High throughput multi sample tissue grinding system
test tube rack
Workflow:


Overview:
High throughput tissue grinder, also known as bead tissue cell disruptor, multi sample tissue grinder, rapid tissue grinder, multi sample tissue homogenizer, rapid sample homogenization system, rapid nucleic acid extractor, multifunctional homogenizer.
This product adopts microcomputer software control program; The parameter settings are simple and intuitive, and the operation is smooth. It is a specialized equipment that can quickly process various products at once in fields such as scientific research, biomedicine, food testing, and universities.
Multiple samples are ground quickly and effectively simultaneously. It can be dry ground, wet ground, mixed, and homogenized. For extracting nucleic acids from high-throughput samples, it can greatly improve grinding efficiency and quality. The high-throughput tissue grinder uses a closed disposable centrifuge tube during the grinding process, effectively avoiding sample cross contamination. Setting the same grinding procedure for the same tissue sample can achieve the same grinding efficiency and improve the repeatability between samples. Due to the use of grinding balls for grinding, the grinding of the sample is more uniform and thorough compared to traditional grinding methods. Using a high-throughput tissue grinder, it can also be used as a homogenizer to quickly disperse samples using stainless steel balls, high-density glass beads, or zirconia beads. The sample temperature does not rise during the grinding and homogenization process, and the speed can be adjusted.
As a new generation of tissue grinders, multi sample tissue grinders have irreplaceable advantages.

Principle:
Vertical up and down oscillation mode, the oscillation system undergoes high-frequency reciprocating motion, causing the frozen sample in the grinding tube to collide with the grinding ball. The resulting grinding shear force and impact force completely break the tissue.

Application scope:
◆ Organization homogenization, grinding, cell lysis, homogenization, material dispersion, preparation, sample mixing, oscillation
Grinding and crushing of various plant tissue samples including roots, stems, leaves, flowers, fruits, seeds, etc
Grinding and crushing of various animal tissues including brain, heart, lungs, stomach, liver, thymus, kidneys, intestines, lymph nodes, muscles, bones, and other samples
Grinding and crushing of samples such as fungi and bacteria
Grinding and crushing for analysis and testing of food and drug ingredients
Grinding and crushing of volatile samples including coal, oil shale, wax products, etc
Grinding and crushing of samples of plastics, polymers including PE, PS, textiles (yarn), resins, etc
Product Features:
Vertical up and down vibration mode, achieved quickly through high-frequency reciprocating vibration, impact, and shearing of grinding beads (zirconia, steel beads, glass beads, ceramic beads)
High efficiency in quantity: 2 × 24, 2 × 48, and 4 × 96 samples can be ground within 1 minute. There is little difference between batches and within batches. The extracted protein has a higher specific activity and longer nucleic acid fragments
◎ No cross contamination, no loss of samples: The sample tube is in a fully enclosed state during the crushing process, and disposable centrifuge tubes and beads can be used. The samples are kept intact in the tube to avoid cross contamination between samples and external contamination. The ground and crushed samples can be directly cracked and centrifuged without sample loss
Easy to operate: microcomputer control, user-friendly touch screen interface, 5.7 "TFT LCD screen, displaying working status, built-in program controller, can set parameters such as grinding time and rotor vibration frequency
◎ Good stability: Adopting vertical oscillation mode, grinding is more thorough, and stability is better
During the operation of the instrument, the noise level is less than 65dB and will not interfere with other experiments or instruments
◎ Convenient low-temperature operation: When a low-temperature grinding environment is required, the adapter containing the sample can be immersed in liquid nitrogen and cooled for 1-2 minutes. After removal, it can be quickly fixed on the host to start grinding without the need for further freezing treatment, saving liquid nitrogen
Good repeatability: Setting the same procedure for the same tissue sample can achieve the same grinding effect. Short working hours, sample temperature will not rise
◎安全性高：
● Tightening device with automatic center positioning
The system has a self checking function
● Equipped with safety doors and locks

Technical Specifications:
Standard configuration: Two adapter specifications are available for selection
Homogenization speed: 10-70HZ, i.e. 300-2100 revolutions per second
Anti vibration principle: German patent schleifen-1 working mode
Adapter material: Polytetrafluoroethylene
Grinding methods: wet grinding, dry grinding, low-temperature grinding are all acceptable
Maximum feed size: No requirements, adjust according to adapter
Final discharge particle size:~5 µ m
Number of grinding platforms: (Acceptable number of grinding tanks)>2
Grinding kit material: hard rigid, polytetrafluoroethylene (PTFE)
Grinding ball diameter: 0.1-30mm
Grinding ball materials: alloy steel, chromium steel, zirconia, tungsten carbide, quartz sand;
Acceleration and deceleration: reach maximum and minimum speeds within 2 seconds
Working time: 0 seconds to 99 minutes, customizable
Noise level:<65db
Power supply: 220V/50HZ
★ Conventional adapters can be placed in the refrigerator to provide a cold environment for the sample during operation, and can be equipped with a cooling adapter that can be soaked in liquid nitrogen for more than 30 minutes
★ Randomly select 1000 5mm stainless steel bulbs
The noise emission value for the working environment depends on the type of sample and the setting of the grinder. The parameters in the table are in the unloaded state, and a small amount of samples commonly used for DNA and RNA separation can be prepared in disposable centrifuge tubes. An adapter made of polytetrafluoroethylene material can be used to accommodate 5 or 10 disposable sample tubes for cell lysis. In the multi sample tissue grinder, cell tissue is rapidly and effectively fragmented in a very short period of time, thus eliminating the need for additional low-temperature refrigeration

Basic Parameters:

model	Processing sample size	Dimensions (mm)	Weight (kg)
VKZY-24	24*（0.2-0.5ML）/16*2ML/4*(5-10)ML / 2*50ML	280*400*530	35
VKZY-48	48*（0.2-0.5ML）/24*2ML/12*(5-10)ML/2*50ML	400*340*530	40
VKZY-192	192*（0.2-0.5ML）/48*2ML /24*(5-10)ML/4*50ML	480*420*575	55
VKZY-384	384*（0.2-0.5ML）/96*2ML/48*(5-10)ML/8*50ML	480*420*575	55

Operation steps:
1. Add the processed sample and grinding ball into the centrifuge tube in sequence
2. Place the centrifuge tube containing the sample into the adapter
3. Freeze the adapter with the sample in liquid nitrogen for a few minutes
4. Place the frozen sample and adapter in the middle of the fixture and adjust their position
5. Place the fixture on the sample stage, position the slot, tighten the vertical positioning knob, and return the safety lock to its original position
6. Cover the safety door of the machine
7. Set vibration frequency and vibration time
8. Start the machine and perform the crushing process
9. Wait for the machine to completely stop vibrating before shutting down, opening the safety door, and taking out the sample
10. Instrument repositioning

Notes:
1. The instrument should be placed in a dry and ventilated environment for use
2. The sample is symmetrically distributed in the sample holder to ensure its balance
3. Before closing the safety door, it is necessary to confirm that the fixture is completely fixed and there is no looseness
When setting the oscillation frequency, it should not exceed the maximum range of 1500 times/min
When freezing the sample, attention should be paid to preventing liquid nitrogen from splashing out and causing frostbite


Attention: The operation steps and precautions are not included in the color page, only on the website